Prevalence of Neuropathy in Diabetic Polulation and Role of Insulin on NRG - 1 Gene Expression in Brain Regions of Diabetic Rats

Abstract

First and foremost I dedicate my sincere thanks to God with pure heart and soul. He always leads me to a right path and gives me enough strength to reach all success. I wish to be strengthened by divine grace forever. I especially want to thank Dr. Amee K. Nair, Asst. Professor, I S N U for her enormous support, innocent caring, inspiration and motivation throughout my dissertation and enriched my career as a good student. I record my gratitude to the entire subject and the hospital staffs of Gayatri Mandir Trust Hospital (Shahibaug), Shri Kanti Manilal Trust Hospital (Shahibaug), Police Commissioner's Hospital (Shahibaug) and Rajasthan hospital. We thank Dr. Kiran K. Shah, Dr. N.D Khimesra, Dr. K.D Tiberwala, Dr. Bharat Shah and Dr. Faruk Memon, for their help and creative suggestion. We extend our thanks to Dr. Anil Chadha, Director Rajasthan hospital and his team of doctors for giving us all the necessary facilities and invaluable advice in the fulfillment of our demographic studies. It’s my great honour to thank Prof. Sarat Dalai Director (I/c), Institute of Science, Nirma University for his valuable advice, motivation and critical suggestions and for providing me with all the facilities in the institute for the successful completion of this project. I express my gratitude to all the faculty members of the Institute of Science, Dr. Shalini Rajkumar, Dr. Sriram Seshadri, Dr. Nasreen Munshi, Dr. Mili Das, Dr. Vijay Kothari, Dr. Sonal Bakshi, for their unconditional support and valuable time. I want to thanks to Mr. Sachin Prajapati, Mr. Bharat Anand, Mr. Hasit Trivedi and all other non-teaching staff for their co-operation during my dissertation work. Practical work in laboratory would not have been possible without their valuable support. I would like to thank all Research scholars Mr. Rahul Jog, Ms. Harshita Chaudhary, Mr. Mahendrapal Singh Rajput, Mr. Maharshi Pandya, Mr. Prashant Jena, Mrs. Kaveri Purandhar and Mrs. Disha Trivedi for their valuable support and share their working experiences throughout my dissertation work. I would like to thank my project mate Aditi Mathur and all other group members Abhishek Agarwal, Mukesh Kumar Jat, Anand nakhva and Swati Mittal for their great support and without their valuable support this project may not be complete. I would like to thank all my friends Hardik Patel, Palak Patel, Purvi Zaveri, Arpita Maheshwary, Suhani Palkhiwala, Arpan Bhatt, Abhishek Mandal, Hardik Goswami, Chinmay Goyal, Utkarsh Patel, Manan Trivedi, Chandra prakhash Sharma, Suresh Kumar, Ankit Gupta, Rajesh Parmar, Puspendra Sahu, Rinu Shahni and Dhara Hathiwala for their care and unconditional support which helped to face any situation with ease. Also, I will always cherish those moments which spent with them with all of us being together. My sincere thank to all the teachers of my schools and college who help me to mould my career. Their great knowledge, encouragement and powerful motivation make my strong back bone of education. I personally feel that, teachers are the main source for sowing quality seeds of knowledge in children’s mind and the source for motivation and enthusiasm towards learning and studies. I want to express my gratitude to my family members. I lovingly acknowledge my parents Shri Surya Prakash Trivedi (Papa) and Smt. Kiran Devi (Mummi), my grandparents Shri Behari Lal Sharma (Dada ji) and Smt. Gaindi Devi (Dadi ji). It’s my pleasure to acknowledge my brothers Niranjan Sharma, Pramod Sharma, Pradeep Sharma, Himanshu Sharma and Shashank Sharma and my sisters Anita Sharma and Pallavi Sharma. I want to dedicate my all success to my family. Their innocent caring, eternal blessings, motivation and constant encouragement throughout my life make me enormously strong and able. I personally feel that, their divine blessings play a very critical role in my all success. Last but not the least, my sincere thank to all those who have not been mentioned by name but nevertheless have been of invaluable help in my dissertation work.