IR @ Nirma University
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http://10.1.7.192:80/jspui/handle/123456789/5376| Title: | Understanding the Role of Heat Shock Protein Isoforms in Male Fertility, Aging and Apoptosis |
| Authors: | Seshadri, Sriram Purandhar, Kaveri Jena, Prasant Kumar Prajapati, Bhumika Rajput, Parth |
| Keywords: | Aging Heat-shock proteins Infertility Male Mitochondria Apoptosis |
| Issue Date: | Dec-2014 |
| Publisher: | World J Mens Health |
| Abstract: | Heat shock proteins (HSPs) play a role in the homeostasis, apoptosis regulation and the maintenance of the various other physiological processes. Aging is accompanied by a decrease in the resistance to environmental stress, while mitochondria are primary targets in the process of aging, their expression decreasing with age. Mitochondrion also plays a significant role in the process of spermatogenesis. HSPs have been shown to be involved in apoptosis with some of acting as apoptotic inhibitors and are involved in cytoprotection. In this review we discuss the roles of Hsp 27, 60, 70, and 90 in aging and male infertility and have concluded that these particular HSPs can be used as a molecular markers for mitochondrially- mediated apoptosis, aging and male infertility. |
| Description: | 32(3): 123-132 |
| URI: | http://hdl.handle.net/123456789/5376 |
| ISSN: | 2287-4690 |
| Appears in Collections: | Faculty Papers |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2014 Purandhar et al 2014.pdf | 94 | 859.65 kB | Adobe PDF |  View/Open |
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