In Vitro Antibacterial Activity of Emblica officinalis and Tamarindus indica Seed Extracts against Multidrug Resistant Acinetobacter baumannii

Abstract

Seed extracts of Emblica officinalis, Tamarindus indica, Sygyzium cumini, and Manilkara zapota, prepared in methanol, acetone, and ethanol using microwave assisted extraction method, were evaluated by broth dilution assay for their antibacterial property against multiple strains of Acinetobacter baumannii, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Candida albicans isolated from hospital patients admitted in intensive care unit. E. officinalis and T. indica extracts exerted bacteriostatic activity against A. baumannii with minimum inhibitory concentration values ranging from 500-750 μg/mL. Total activity of the potent extracts was found to have a positive linear correlation with the extraction efficiency.