Design of HVAC System for Clean Room and Highly Potent Drug

Abstract

Heating ventilation and air conditioning (HVAC) plays an important role in modern building structures. HVAC is an important system for controlling of temperature, relative humidity and to maintain the specified conditions. Components like variable air volume and thermosts are used to control Fuctuation of air volume entering with the help of valves, dampers and hence used to get higher energy efficiency. Air handling unit maintains flow of air with required conditions. In the present study, HVAC system is designed for clean room and highly potent drug to control viable and non-viable particles, temperature, relative humidity, hygiene zone for different process area as per drug regulation. The methodology of design follows architectural layout study, area classification and pressure zoning, air handler zoning and calculations with design qualification sheet. Sensible as well as latent heat loads were considered in the calculations of capacity of air handling unit. The ASHRAE and Good Manufacturing Practices (GMP) guidelines were followed in the design. In the design, diversity factor and bypass factor were considered as 70% and 5% respectively. The total dehumidified rise was considered for summer and monsoon and was compensated by cooling coil. From the design, total reheat capacity and total chilling capacity were found as 84 kW and 542 TR respectively.