Please use this identifier to cite or link to this item: http://10.1.7.192:80/jspui/handle/123456789/7266
Full metadata record
DC FieldValueLanguage
dc.contributor.authorSimon, Chris V.-
dc.date.accessioned2016-12-08T08:57:30Z-
dc.date.available2016-12-08T08:57:30Z-
dc.date.issued2016-05-
dc.identifier.urihttp://hdl.handle.net/123456789/7266-
dc.description.abstractMoisturizers are among the most commonly used cosmetic product in everyday life. The characteristics of an ideal moisturizer are: S.C hydration and decrease TEWL thus increases in smoothness and softness of skin. This aids in the replenishment of lipid barrier and increases the skin’s natural moisture mechanism. The natural ingredients are added to product to enhance the moisturizing activity of the cosmetic products as they are considered to be safe and popular too. The purpose of this present investigation is to design and evaluate an emulsified, low pH cosmetic composition having improved thermal stability and improved pH stability, in particular, the emulsified, low pH cosmetic composition having a pH of about 3.7 to about 4.5 and evaluate its moisturizing effects containing active Aquaxyl (Xylitylglucoside, Xylitol, Anhydroxylitol) by in-vitro skin testing methods. AQUAXYL is a derivative of two plant sugars, xylitol and glucose. Its mode of action, reinforces the antidehydration shield (Loricrin, essential lipids) together with the activation of water reserves (hyaluronic acid booster) and their movement (Aquaporins, Tight Junctions). It improves water reserves and limits water loss. The trial batches are evaluated for phyisco-chemical properties such as specific gravity, Loss on drying (LOD), Viscosity, Thermal stability, Microbial testing, Sensory analysis, In-Vitro Corneometry skin testing study. The study was conducted during the spring months (January to May). A total of five healthy male volunteers aged 55 to 65 years contributed to accomplish this study. The active cream was applied to the face (cheeks) for a duration of 1 week. The instrumental measurements were done using a corneo-meter in environmentally controlled room, with controlled temperature (18.0 to 20.6°C) and relative humidity (55 to 65%). The results recommended that the assessed outcome was very well accepted, having improved pH stablility and improved storage stability, along with improved skin hydration and skin barrier function by the product.en_US
dc.publisherInstitute of Pharmacy, Nirma University, A'baden_US
dc.relation.ispartofseriesPDR00435-
dc.subjectMoisturizeren_US
dc.subjectAged Skinen_US
dc.subjectSenior Citizenen_US
dc.subjectLow pHen_US
dc.subjectAquaxyl (Xylitylglucoside, Xylitol, Anhydroxylitol)en_US
dc.subjectEmulsionsen_US
dc.subjectCorneometeren_US
dc.subjectPDR00435en_US
dc.titleDesign and Evaluation of Face Moisturizer with Specific Needs of Senior Citizenen_US
dc.typeDissertationen_US
Appears in Collections:M.Pharm Research reports

Files in This Item:
File Description SizeFormat 
PDR00435.pdfPDR004352.97 MBAdobe PDFThumbnail
View/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.