IR @ Nirma University
Keeping in tune the global developments we are creating an institutional repository using DSpace Software (Digital Library Software). We are archiving institutional knowledge like, faculty papers, theses, and dissertations in PDF format at DSpace. Students can access this digital information anywhere in the campus.
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http://10.1.7.192:80/jspui/handle/123456789/9775| Title: | Newer Therapeutic Targets for Parkinson Disease |
| Authors: | Gandhi, Samkit S. |
| Keywords: | PPR01019 B. Pharm Project Report Pharmacology Parkinson’s diseases Pathogenesis Therapeutic targets α-synuclein Kinase Dopamine PPARγ, |
| Issue Date: | May-2020 |
| Publisher: | Institute of Pharmacy, Nirma University, A'bad |
| Series/Report no.: | PPR01019; |
| Abstract: | Parkinson’s disease (PD) occurs mainly at an elderly age. It is the second most occurring neurodegenerative progressive disorder of movement. It is due to aggregation of α-synuclein (a protein normally involved in vesicle recycling) in the form of characteristic Lewy bodies. There are many therapeutic targets available for treatment of PD like α-7 nicotinic receptors, PPARγ and PGC-1α, misfolded α-synuclein and toll-like receptors, the transcription factor Nrf2, mixed lineage kinase(MLK)– c-jun n-terminal kinase (JNK) signaling pathway are the 5 target of therapeutic that has been discussed in this review article. |
| Description: | Guided by Dr. Bhagwati Saxena |
| URI: | http://10.1.7.192:80/jspui/handle/123456789/9775 |
| Appears in Collections: | B. Pharm Project Reports |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| PPR01019.pdf | PPR01019 | 2.21 MB | Adobe PDF |  View/Open |
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