Exploring the Role of Finger Millet in Diabetic Wound Healing Film

Abstract

Diabetes has become one of the biggest diseases affecting people, worldwide there are 143 million diabetes patients and India is stated as the Hub of diabetes, with around 77 million people suffering from diabetes. The prevalence of type 1 diabetes is seen in children and is not associated with the lifestyle but type 2 diabetes which affects the major chunk of population can be associated with the modern life style. In patients with diabetes mellitus, chronic wounds frequently develop because of reduced wound healing capacity. Chronic and resilient wounds that are usually found on these patients' feet are one of these issue, these are known as the Diabetic foot ulcers which are deep with neuropathy and cause the ulcer to turn into gangrene which can lead to amputation. A number of clinical studies have been undertaken which have shown that deficit of protein, carbohydrate, vitamins, minerals and fats can reduce wound healing ability. Returning to the wound healing phase of both regular and diabetic patients. Finger millet (Eleusine coracana) commonly known as Ragi and easily cultivated cereal and has an abundance in India, has shown to provide all the nutrition and have the wound healing property on topical applications on the wound. Finger millets. In aspects of its nutritional property it contains calcium which also aids into diabetic wound healing. Also the polyphenols act as antioxidants, anti-inflammatory, anti-microbial, which can contribute in healing diabetic wounds. Incorporation of finger millets into modern dressing materials such as wound healing films can show improvement of DFUs.These wound healing films either made up of polymers or hydrogels, such films promise to maintain proper moisture keeping the vapours out and allowing the entry of oxygen entry to the wound site allowing the wound to dry up and not form exudates which can harbour bacteria. This report includes a brief about finger millets, nutritional and other therapeutic aspects, its wound healing properties, extraction process, incorporation of its phytoconstituents, the variety of wound healing films, their evaluation parameters.