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Title: | Pharmacokinetic Study Of Progesterone Capsules In Post Menopausal Females Of India Under Fasting Condition |
Authors: | Panchal, Shital, J Patel, Jagruti, A |
Keywords: | Pharmacokinetic Progesterone Post menopausal females of India LCMS-MS |
Issue Date: | 2009 |
Publisher: | University of Salerno |
Abstract: | The study was conducted to assess the pharmacokinetics of micronized progesterone administered in the capsule form. Ten post-menopausal females of India, with a mean age of 51.50 years, volunteered to participate in the study. The pharmacokinetics of 200 mg of progesterone evaluated by validated Liquid Chromatography Mass Sepectroscopy-Mass spectroscopy (LCMS-MS) method. After the initial administration of 200 mg, a mean serum Cmax of 3.59±0.66 was reached at a tmax of 3.50±0.59. The terminal half-life (t1/2) was 7.09±2.52. Micronized progesterone given as a capsule is well tolerated, safe and an easily administered. Key Words: Pharmacokinetic, Progesterone, Post menopausal, females of India, LCMS-MS |
Description: | Pharmacologyonline 3 , 2009, Page No. 1037-1046 |
URI: | http://hdl.handle.net/123456789/2105 |
Appears in Collections: | Faculty Papers |
Files in This Item:
File | Description | Size | Format | |
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IPFP0008.pdf | IPFP0008 | 1.03 MB | Adobe PDF | ![]() View/Open |
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