IR @ Nirma University
Keeping in tune the global developments we are creating an institutional repository using DSpace Software (Digital Library Software). We are archiving institutional knowledge like, faculty papers, theses, and dissertations in PDF format at DSpace. Students can access this digital information anywhere in the campus.
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http://10.1.7.192:80/jspui/handle/123456789/3152| Title: | Reversed-Phase high performance liquid chromatographic (RP_HPLC) method for determination of tacrolimus in bulk and pharmaceutical formulation |
| Authors: | Patel, Pranav Panchal, Shital J. Mehta, Tejal A. |
| Keywords: | Tacrolimus RP-HPLC Faculty Paper Pharmacy Faculty Paper |
| Issue Date: | 2011 |
| Publisher: | International Journal of Pharmacy and Pharmaceutical sciences |
| Series/Report no.: | IPFP0059 |
| Abstract: | An accurate, simple, and reproducible liquid chromatographic method was developed and validated for the determination of Tacrolimus in capsules. The analysis was performed at ambient temperature on a reversed-phase C18 column with UV detection at 213 nm. The mobile phase was acetonirile (100 %) used at a constant flow rate of 0.9 ml/min. The method was validated in terms of linearity, precision, accuracy, and specificity .The response was linear in the range of 5-250 μg/ml (r2= 0.9978). The relative standard deviations for intra- and inter-day precision studies were found to be less than 2% with 98.90 to 101.12% accuracy, respectively. |
| Description: | International Journal of Pharmacy and Pharmaceutical sciences 9(4):220-222, 2011 |
| URI: | http://10.1.7.181:1900/jspui/123456789/3152 |
| Appears in Collections: | Faculty Papers |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IPFP0059.pdf | IPFP0059 | 217.85 kB | Adobe PDF |  View/Open |
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